Senou Natsuru is a normal high school boy. One day he wakes up to find himself turned into a girl. A stuffed tiger “Harakiri Tora” comes to life and tells him to fight as a female psychic fighter “Kämpfer”. Having no idea about what’s going on, Natsuru is involved in the battles against other “Kämpfer”. “Kämpfer” is the German word for “fighter”.